Caryophyllene oxide is a natural sesquiterpene often found in essential oils like clove, hops, and rosemary. While often overshadowed by its parent compound, Beta-Caryophyllene, the oxide form offers a unique profile of stability and therapeutic potential. In this guide, we dive into the latest research regarding its industrial and health applications.

Unlike many volatile terpenes, Caryophyllene oxide is known for its oxidative stability. This makes it a preferred ingredient in the fragrance and cosmetic industries. Chemically, it is the metabolic byproduct of the oxidation of Beta-Caryophyllene, yet it retains significant biological activity, particularly as an antifungal and anti-inflammatory agent.
| Property | Specification |
|---|---|
| Chemical Formula | C15H24O |
| Molecular Weight | 220.35 g/mol |
| Appearance | White crystalline solid/powder |
| Solubility | Soluble in alcohol and oils |
Recent studies have highlighted the versatility of Caryophyllene oxide. Its primary strengths lie in its ability to act as a preservative and a therapeutic enhancer. Below are the key areas where this compound excels:
Antifungal Properties: Widely used in topical treatments to combat fungal infections.
Food Flavoring: Approved as a flavoring agent, providing woody and spicy notes.
Preservative Qualities: Enhances the shelf-life of essential oil blends by preventing degradation.
If you are looking for high-purity ingredients for your formulation, you can buy Caryophyllene oxide from our certified facility, ensuring consistent quality for your R&D needs.

Unlock the potential of stabilized terpenes in your products. We provide bulk supply with full COA documentation.
No. While they are related, Caryophyllene oxide is the oxidized version. It is more stable and has a different crystalline structure compared to the liquid state of Beta-Caryophyllene.
Yes, Caryophyllene oxide is commonly used in cosmetics and perfumes. It is valued for its fixative properties, helping scents last longer on the skin.
It has a distinct woody, slightly spicy, and dry aroma, making it a staple in woody perfume bases and masculine scents.